A subset of Sjögren's syndrome associates with the TCRBV13S2 locus but not the TCRBV2S1 locus.

doi:10.1016/0198-8859(94)00115-7

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Article

A subset of Sjögren's syndrome associates with the TCRBV13S2 locus but not the TCRBV2S1 locus.

Human immunology - 1 Apr 1995

Kay R A, Hutchings C J, Ollier W E

Abstract excerpt

HGPSS associates with the TCRBV6S7 locus within the TCR beta-chain gene complex. However, V beta 6.7 T cells, encoded by this locus, have never been implicated in the salivary gland destruction that characterizes primary Sjögren's syndrome. Both V beta 13 and V beta 2 T cells have been implicated...

Topics

Base Sequence
Genotype
Humans
Molecular Sequence Data
Receptors, Antigen, T-Cell, alpha-beta
Sjogren's Syndrome

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