Article
Comparison of HLA class II genes in Caucasoid, Chinese, and Japanese patients with primary Sjögren's syndrome.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 1993
Kang H I, Fei H M, Saito I, Sawada S, Chen S L, Yi D, Chan E, Peebles C, Bugawan T L, Erlich H A
Abstract excerpt
To better define the genetic factors that predispose to primary Sjögren's syndrome (SS), we have used polymerase chain reaction in combination with oligonucleotide probe hybridization and DNA sequencing to analyze HLA-DRB1, -DQA1, -DQB1, and -DPB1 alleles in Caucasoid (California), Japanese (Tokyo), and Chinese (Shanghai and Beijing) SS patients. In comparison to local controls in each region, we found: 1)...
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