Article
Salivary gland lymphomas in patients with Sjögren's syndrome may frequently develop from rheumatoid factor B cells.
Arthritis and rheumatism - 1 Apr 2000
Martin T, Weber J C, Levallois H, Labouret N, Soley A, Koenig S, Korganow A S, Pasquali J L
Abstract excerpt
OBJECTIVE: Patients with Sjögren's syndrome (SS) have an increased risk of developing monoclonal B cell non-Hodgkin's lymphomas (MNHL), which frequently occur in the salivary glands (SG). The transition from the benign lymphocyte infiltrate of the gland that characterizes SS to MNHL is not well understood. Previous sequence analyses of the expressed variable (V) region genes have supported the theory that the...
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