Association of a 5-HT1Dbeta receptor gene polymorphism with obsessive-compulsive disorder in Korean male subjects.

Abstract excerpt

The 5-HT1Dbeta receptor gene appears to be particularly interesting in the pathophysiology of obsessive-compulsive disorder (OCD). The 5-HT1Dbeta receptor is a terminal autoreceptor involved in the regulation of serotonin synthesis and release. We performed an association study of the G861C single nucleotide polymorphism (SNP) of the 5-HT1Dbeta receptor in 167 male Korean OCD subjects and in 107 controls....

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