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Article

A transcribed polymorphism and sub-localisation of MDM2.

Human genetics - 1 May 1994

Heighway J, Mitchell E L, Jones D, White G R, Santibáñez Koref M F

Abstract excerpt

An NlaIV polymorphism in the 5' untranslated region of the MDM2 gene is described. MDM2 was sublocalised by fluorescence in situ hybridisation with a yeast artificial chromosome probe to 12q14.3-12q15. We demonstrate the use of the polymorphism to assess allelic imbalance in breast tumours.

Topics

Alleles
Base Sequence
Breast Neoplasms
DNA Primers
Female
Humans
In Situ Hybridization, Fluorescence
Molecular Sequence Data
Neoplasm Proteins
Nuclear Proteins
Polymerase Chain Reaction
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins

Proto-Oncogene Proteins c-mdm2

Saccharomyces cerevisiae

Source

Identifiers

PMID: 8168847
DOI: 10.1007/BF00202837

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8168847-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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