Molecular mechanisms of olfactory neuronal gene regulation.

Abstract excerpt

The mammalian olfactory system utilizes a biochemical cascade mediated by specialized proteins to detect odorants with high sensitivity and specificity. The recent identification of olfactory neuron-specific components for each step in the signalling cascade suggests that expression of these proteins is coordinately controlled by cis-acting regulatory sequences and trans-acting transcriptional activators. We have...

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