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Article

Genome-wide allelotypes of familial pancreatic adenocarcinomas and familial and sporadic intraductal papillary mucinous neoplasms.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2007

Abe Tadayoshi, Fukushima Noriyoshi, Brune Kieran, Boehm Corinne, Sato Norihiro, Matsubayashi Hiroyuki, Canto Marcia, Petersen Gloria M, Hruban Ralph H, Goggins Michael

Abstract excerpt

PURPOSE: Most familial cancer susceptibility genes are tumor suppressor genes that are biallelically inactivated in familial neoplasms through somatic deletion of the wild-type allele. Identifying the genomic losses that occur in pancreatic neoplasms, particularly those that occur in familial and precursor neoplasms, may help localize the genes responsible for pancreatic cancer susceptibility. EXPERIMENTAL...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 17947463
DOI: 10.1158/1078-0432.CCR-07-0471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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