Article
CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma.
Nature - 5 May 1994
Mandelboim O, Berke G, Fridkin M, Feldman M, Eisenstein M, Eisenbach L
Abstract excerpt
Many mouse and human tumours express major histocompatibility complex (MHC) class I-associated antigens that constitute targets for syngeneic cytotoxic T lymphocytes (CTL). Genes encoding such antigens were isolated from a mouse mastocytoma and from human melanomas by genetic methods. Isolation and characterization of MHC class I-associated peptides has enabled specific anchor residues to be identified that are...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Neoplasm
- Connexins
- H-2 Antigens
- Lung Neoplasms
- Mice
- Mice, Inbred C57BL
- Mice, Nude
- Molecular Sequence Data
- Mutation
- Neoplasm Proteins