Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TAP2D is associated with HLA-B44 and DR4 and may contribute to rheumatoid arthritis and Felty's syndrome susceptibility.

Clinical and experimental rheumatology - 1 Jan 2000

Hillarby M C, Davies E J, Donn R P, Grennan D M, Ollier W E

Abstract excerpt

OBJECTIVES: TAP2 transporter gene polymorphisms have been ascertained in patients with rheumatoid arthritis (RA) and Felty's syndrome (FS) to determine whether particular alleles of this gene are disease associated. METHODS: TAP2 dimorphisms at amino acid positions 379, 565 and 665 were detected using ARMS-PCR in 89 RA patients, 24 FS patients and 64 control subjects. TAP 2 alleles were assigned from these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acids
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haplotypes

Share to Major Histocompatibility Complex

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 8697660

Genes

TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TAP2D is associated with HLA-B44 and DR4 and may contribute to rheumatoid arthritis and Felty's syndrome susceptibility.PMID 8697660Read ↗

Significant association between TAP2 polymorphisms and rheumatoid arthritis: a meta-analysis.Semantic proximity Read ↗

Association of TAP2 polymorphism with rheumatoid arthritis is secondary to allelic association with HLA-DRB1.Semantic proximity Read ↗

Analysis of the MHC-encoded transporters TAP1 and TAP2 in rheumatoid arthritis: linkage with DR4 accounts for the association with a minor TAP2 allele.Semantic proximity Read ↗

TAP1 and TAP2 gene polymorphism in rheumatoid arthritis in a population in eastern France.Semantic proximity Read ↗

Tap gene associations in UK caucasoids.Semantic proximity Read ↗

Genetic association between TAP1 and TAP2 polymorphisms and ankylosing spondylitis: a systematic review and meta-analysis.Semantic proximity Read ↗

Polymorphisms in the TAP2 gene and their association with rheumatoid arthritis.Semantic proximity Read ↗

Polymorphism of human major histocompatibility complex-encoded transporter associated with antigen processing (TAP) genes and susceptibility to juvenile rheumatoid arthritis.Semantic proximity Read ↗

TAP2 alleles in inflammatory arthritis.Semantic proximity Read ↗

TAP1 and TAP2 polymorphisms analysis in northwestern Colombian patients with systemic lupus erythematosus.Semantic proximity Read ↗

Absence of TAP 2D in Yoruba Nigerians.Semantic proximity Read ↗

Correlations and Influence of TAP2 Genes Polymorphisms and Systemic Lupus Erythematosus Propensity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.