Nonmutagenic carcinogens induce intrachromosomal recombination in dividing yeast cells.

doi:10.1289/ehp.93101s5179

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Article

Nonmutagenic carcinogens induce intrachromosomal recombination in dividing yeast cells.

Environmental health perspectives - 1 Dec 1993

Schiestl R H

Abstract excerpt

A large number of animal and human carcinogens without apparent genotoxic activity exist (nonmutagenic carcinogens) that are difficult or impossible to detect with the currently used short-term tests. Because of the association of carcinogenesis with genome rearrangement, a system selecting for i...

Topics

Animals
Carcinogens
Cell Cycle
Cell Division
Chromosomes, Fungal
Gene Rearrangement
Humans
Mutation
Recombination, Genetic
Saccharomyces cerevisiae

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