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Article

Nonmutagenic carcinogens induce intrachromosomal recombination in dividing yeast cells.

Environmental health perspectives - 1 Dec 1993

Schiestl R H

Abstract excerpt

A large number of animal and human carcinogens without apparent genotoxic activity exist (nonmutagenic carcinogens) that are difficult or impossible to detect with the currently used short-term tests. Because of the association of carcinogenesis with genome rearrangement, a system selecting for intrachromosomal recombination (DEL recombination) that results in genome rearrangement has been constructed in the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8013407
DOI: 10.1289/ehp.93101s5179
PMCID: PMC1519453

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Source receipt: pubmed, retrieved 7 Sept 2026.

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