De novo synthesis of thymidylate via deoxycytidine in dcd (dCTP deaminase) mutants of Escherichia coli.

doi:10.1128/jb.176.8.2194-2199.1994

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Article

De novo synthesis of thymidylate via deoxycytidine in dcd (dCTP deaminase) mutants of Escherichia coli.

Journal of bacteriology - 1 Apr 1994

Weiss B, Wang L

Abstract excerpt

dcd (dCTP deaminase) mutants of Escherichia coli were reported not to require thymidine for growth even though most of the thymidylate that is synthesized de novo arises from cytosine nucleotides through a pathway involving dCTP deaminase. We found, however, that the fresh introduction of dcd mut...

Topics

Anaerobiosis
Bromodeoxyuridine
Deoxycytidine
Escherichia coli
Genes, Bacterial
Genetic Complementation Test
Mutation
Nucleotide Deaminases
Pentosyltransferases
Pyrimidines
Thymidine Monophosphate
Thymidine Phosphorylase
Uridine Phosphorylase

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