Article
Simplifying genetic locus assignment of HLA-DRB genes.
Immunology today - 1 Feb 1994
Andersson G, Andersson L, Larhammar D, Rask L, Sigurdardóttir S
Abstract excerpt
The DR haplotypes of the human major histocompatibility complex have been arranged in five haplotypic groups based on genomic cloning and sequence analyses. To date, the expressed DRB sequences have been assigned to four different loci: DRB1, 3, 4 and 5. DRB1 alleles are present in all haplotypes, whereas DRB3, 4 and 5 are present only in some haplotypes. Here, Göran Andersson and colleagues suggest that DRB3, 4...
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