Article
Cytosolic 5'-nucleotidase/nucleoside phosphotransferase: a nucleoside analog activating enzyme?
Journal of biochemical toxicology - 1 Feb 1994
Turriani M, Pesi R, Nardone A, Turchi G, Sgarrella F, Ipata P L, Tozzi M G
Abstract excerpt
Nucleoside phosphotransferase acting on inosine and deoxyinosine has been partially purified from cultured Chinese hamster lung fibroblasts (V79). The activity is associated with a cytosolic 5'-nucleotidase acting on IMP and deoxyIMP. The transfer of the phosphate group from IMP to inosine cataly...
Topics
- 5'-Nucleotidase
- Adenosine Triphosphate
- Animals
- Azaguanine
- Biotransformation
- Cell Line
- Cells, Cultured
- Cricetinae
- Cricetulus
- Cytosol
- Drug Resistance
- Fibroblasts
- Guanosine
- Hypoxanthine Phosphoribosyltransferase
- Inosine
- Inosine Monophosphate
- Male
- Mutation