Expression of a tetrodotoxin-sensitive Na+ current in cultured human retinal pigment epithelial cells.

doi:10.1113/jphysiol.1994.sp020122

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Article

Expression of a tetrodotoxin-sensitive Na+ current in cultured human retinal pigment epithelial cells.

The Journal of physiology - 15 Apr 1994

Wen R, Lui G M, Steinberg R H

Abstract excerpt

We observed a tetrodotoxin (TTX)-sensitive Na+ current in cultured fetal and adult cells of the human retinal pigment epithelium (RPE), but not in any freshly isolated fetal (n = 54) or adult (n = 47) cells, using the whole-cell version of the patch-clamp technique. A similar current was found in...

Topics

Animals
Cell Differentiation
Cell Membrane
Cells, Cultured
Culture Media
Electrophysiology
Humans
Macaca mulatta
Melanins
Phenotype
Pigment Epithelium of Eye
Sodium Channels
Tetrodotoxin

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