Article
Interactions between the gene products of pma1 encoding plasma membrane H(+)-ATPase, and pdr1 controlling multiple drug resistance in Saccharomyces cerevisiae.
Acta biochimica Polonica - 1 Jan 1993
Ułaszewski S
Abstract excerpt
In Saccharomyces cerevisiae, the pma1 mutations controlling the vanadate resistance of the H(+)-ATPase activity from the plasma membrane, map on chromosome VII in the vicinity of pdr1 mutations controlling multiple drug resistance. However, the pma1-1 mutants exhibit a genotype and a multidrug resistant phenotype quite different from those obtained for pdr1 mutants. Quantitative modifications of cycloheximide and...
Topics
- Adenosine Triphosphatases
- Cell Membrane
- Chromosome Mapping
- DNA-Binding Proteins
- Diploidy
- Drug Resistance, Microbial
- Genes, Fungal
- Genotype
- Heterozygote
- Mutation
- Phenotype