Prenatal diagnosis of neonatal alloimmune thrombocytopenia using an allele-specific oligonucleotide probe.

doi:10.1002/pd.1970131106

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Article

Prenatal diagnosis of neonatal alloimmune thrombocytopenia using an allele-specific oligonucleotide probe.

Prenatal diagnosis - 1 Nov 1993

Johnson J M, McFarland J G, Blanchette V S, Freedman J, Siegel-Bartelt J

Abstract excerpt

The prediction of neonatal alloimmune thrombocytopenia (NAIT) in affected families is usually based on information about gene frequencies of the antigen systems involved, parental phenotyping, and fetal platelet counts. Recently the use of allele-specific oligonucleotide probe typing for PlA (HPA...

Topics

Adult
Alleles
Antigens
Female
Humans
Infant, Newborn
Oligonucleotide Probes
Pregnancy
Prenatal Diagnosis
Risk Factors
Thrombocytopenia

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