Article
Prenatal diagnosis of neonatal alloimmune thrombocytopenia using an allele-specific oligonucleotide probe.
Prenatal diagnosis - 1 Nov 1993
Johnson J M, McFarland J G, Blanchette V S, Freedman J, Siegel-Bartelt J
Abstract excerpt
The prediction of neonatal alloimmune thrombocytopenia (NAIT) in affected families is usually based on information about gene frequencies of the antigen systems involved, parental phenotyping, and fetal platelet counts. Recently the use of allele-specific oligonucleotide probe typing for PlA (HPA-1) antigens has been described to determine the risk of second or subsequent fetuses in families where one infant had...
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