Article
Human platelet antigen-1 (Zw) typing of fetuses by analysis of polymerase chain reaction-amplified genomic DNA from amniocytes.
Transfusion medicine (Oxford, England) - 1 Mar 1994
Simsek S, Christiaens G C, Kanhai H H, Beekhuis J R, Bleeker P M, Vlekke A B, Goldschmeding R, von dem Borne A E
Abstract excerpt
Prenatal typing for the human platelet antigens-1 (HPA) permits identification of a fetus at risk for neonatal alloimmune thrombocytopenia (NAITP) in cases of HPA-1 incompatibility in which the father is heterozygous for the HPA-1a antigen. Diagnostic cordocentesis and phenotyping of the fetal platelets are used for this purpose. We applied allele-specific restriction enzyme analysis on polymerase chain reaction...
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