Article
Prenatal testing for hemolytic disease of the newborn and fetal neonatal alloimmune thrombocytopenia - current status.
Expert review of hematology - 1 Dec 2014
Avent Neil D
Abstract excerpt
Incompatibility of red cell and platelet antigens can lead to maternal alloimmunization causing hemolytic disease of the fetus & newborn and fetal neonatal alloimmune thrombocytopenia respectively. As the molecular background of these polymorphisms emerged, prenatal testing using initially fetal DNA obtained from invasively obtained amniotic fluid or chorionic villus was implemented. This evolved into testing...
Topics
- Antigens, Human Platelet
- Blood Group Antigens
- Erythroblastosis, Fetal
- Female
- Genotype
- Humans
- Immunotherapy
- Infant, Newborn
- Integrin beta3
- Pregnancy
- Prenatal Diagnosis
