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Article

The yeast med1 mutant undergoes both meiotic homolog nondisjunction and precocious separation of sister chromatids.

Genetics - 1 Jan 1994

Rockmill B, Roeder G S

Abstract excerpt

A mutant at the yeast MED1 locus was isolated in a screen for sporulation-proficient, meiotic-lethal mutants. Synaptonemal complex formation in the med1 mutant is apparently normal and med1 strains undergo meiotic crossing over at approximately 50% of the wild-type level. The med1 mutant undergoes homolog nondisjunction at meiosis I, presumably as a consequence of the decrease in crossing over. In addition, the...

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Identifiers

PMID: 8138177
DOI: 10.1093/genetics/136.1.65
PMCID: PMC1205793

Genes

MED1

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