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Article

Molecular analysis of the IL-6 receptor in human multiple myeloma, an IL-6-related disease.

FEBS letters - 21 Mar 1994

Rodriguez C, Theillet C, Portier M, Bataille R, Klein B

Abstract excerpt

A PCR-SSCP approach was used to search for mutations in IL-6 receptor genes in 9 human plasma cell lines (HMCL) and in tumor plasma cells from 19 patients with fulminating multiple myeloma, an IL-6-related disease. Whereas no mutation was found in the cytokine receptor homologous (CRH) domain of IL-6R alpha, DNA and RNA polymorphisms in the gp130 CRH domain was detected in tumoral samples as well as in blood...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8137932
DOI: 10.1016/0014-5793(94)80448-6

Genes

CRH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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