Article
Association of IL-6 Promoter and Receptor Polymorphisms with Multiple Myeloma Risk: A Systematic Review and Meta-Analysis.
Genetic testing and molecular biomarkers - 1 Oct 2016
Li Yuying, Du Zhonghua, Wang Xu, Wang Guanjun, Li Wei
Abstract excerpt
BACKGROUND: A number of studies show that the pleiotropic cytokine interleukin-6 (IL-6) plays an important role in the pathogenesis of multiple myeloma (MM). However, whether MM risk is associated with IL-6 genetic variability remains uncertain. OBJECTIVE: The aim of our study was to evaluate the association between two different IL-6 polymorphisms (located in the IL-6 promoter and receptor, respectively) and the...
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