Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of type II polyketide beta-ketoacyl synthase specificity in Streptomyces coelicolor A3(2) by trans complementation of actinorhodin synthase mutants.

Journal of bacteriology - 1 Mar 1994

Kim E S, Hopwood D A, Sherman D H

Abstract excerpt

Complementation of defined actinorhodin beta-ketoacyl synthase (KS) mutants by various other KS genes suggested that the ORF1-encoded KS may be relatively generalized in function, whereas the ORF2-encoded KS component may provide specificity in polyketide chain construction. Evidence for differential temporal-spatial expression of the actinorhodin and spore pigment KSs in Streptomyces coelicolor was obtained.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, Bacterial
Share to Genetic Complementation Test

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Multienzyme Complexes

Share to Mutation

Share to Open Reading Frames

Share to Streptomyces

Share to Transformation, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 8132481
DOI: 10.1128/jb.176.6.1801-1804.1994
PMCID: PMC205275

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of type II polyketide beta-ketoacyl synthase specificity in Streptomyces coelicolor A3(2) by trans complementation of actinorhodin synthase mutants.PMID 8132481Read ↗

Multi-level regulation of coelimycin synthesis in Streptomyces coelicolor A3(2)Semantic proximity Read ↗

Functional complementation of pyran ring formation in actinorhodin biosynthesis in Streptomyces coelicolor A3(2) by ketoreductase genes for granaticin biosynthesis.Semantic proximity Read ↗

Genetic construction and functional analysis of hybrid polyketide synthases containing heterologous acyl carrier proteins.Semantic proximity Read ↗

New classes of Streptomyces coelicolor A3(2) mutants blocked in undecylprodigiosin (Red) biosynthesis.Semantic proximity Read ↗

Differential regulation of antibiotic biosynthesis by DraR-K, a novel two-component system in Streptomyces coelicolor.Semantic proximity Read ↗

Two-Component Systems of Streptomyces coelicolor: An Intricate Network to Be UnraveledSemantic proximity Read ↗

Organisation and functions of the actVA region of the actinorhodin biosynthetic gene cluster of Streptomyces coelicolor.Semantic proximity Read ↗

Targeted gene replacements in a Streptomyces polyketide synthase gene cluster: role for the acyl carrier protein.Semantic proximity Read ↗

Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genesSemantic proximity Read ↗

Identification of a Novel Lincomycin Resistance Mutation Associated with Activation of Antibiotic Production in Streptomyces coelicolor A3(2).Semantic proximity Read ↗

Regulation of sporulation in Streptomyces coelicolor A3(2): a checkpoint multiplex?Semantic proximity Read ↗

DNA sequence and functions of the actVI region of the actinorhodin biosynthetic gene cluster of Streptomyces coelicolor A3(2).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.