DNA sequence and functions of the actVI region of the actinorhodin biosynthetic gene cluster of Streptomyces coelicolor A3(2).

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Article

DNA sequence and functions of the actVI region of the actinorhodin biosynthetic gene cluster of Streptomyces coelicolor A3(2).

The Journal of biological chemistry - 7 Oct 1994

Fernández-Moreno M A, Martínez E, Caballero J L, Ichinose K, Hopwood D A, Malpartida F

Abstract excerpt

Six open reading frames (ORFs) were identified by DNA sequencing of 5.7 kilobase pairs at the left end of the act cluster (the so-called "actVI region"), in the order: ORFB, ORFA, ORF1, ORF2, ORF3, ORF4. ORF1-4 are transcribed rightward and in the same direction as the ORFs of the actVA region wh...

Topics

Amino Acid Sequence
Anthraquinones
Anti-Bacterial Agents
Base Sequence
DNA, Bacterial
Genes, Bacterial
Molecular Sequence Data
Multigene Family
Mutation
Open Reading Frames
Streptomyces

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Open in PubMed

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PMID: 7929165

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7929165-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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