Article
Diversity of pigmentation in cultured human melanocytes is due to differences in the type as well as quantity of melanin.
Pigment cell research - 1 Apr 2006
Wakamatsu Kazumasa, Kavanagh Renny, Kadekaro Ana L, Terzieva Silva, Sturm Richard A, Leachman Sancy, Abdel-Malek Zalfa, Ito Shosuke
Abstract excerpt
Cultured human melanocytes differ tremendously in visual pigmentation, and recapitulate the pigmentary phenotype of the donor's skin. This diversity arises from variation in type as well as quantity of melanin produced. Here, we measured contents of eumelanin (EM) and pheomelanin (PM) in 60 primary human melanocyte cultures (51 neonatal and nine adults), and correlated some of these values with the respective...
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