Article
Variation in Hsp70-1A Expression Contributes to Skin Color Diversity.
The Journal of investigative dermatology - 1 Aug 2016
Murase Daiki, Hachiya Akira, Fullenkamp Rachel, Beck Anita, Moriwaki Shigeru, Hase Tadashi, Takema Yoshinori, Manga Prashiela
Abstract excerpt
The wide range in human skin color results from varying levels of the pigment melanin. Genetic mechanisms underlying coloration differences have been explored, but identified genes do not account for all variation seen in the skin color spectrum. Post-transcriptional and post-translational regulation of factors that determine skin color, including melanin synthesis in epidermal melanocytes, melanosome transfer to...
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