Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional analysis of activins during mammalian development.

Nature - 23 Mar 1995

Matzuk M M, Kumar T R, Vassalli A, Bickenbach J R, Roop D R, Jaenisch R, Bradley A

Abstract excerpt

Activins are dimeric (beta A beta A; beta B beta B; beta A beta B) members of the transforming growth factor-beta superfamily. They are widely expressed during murine development, are highly conserved during vertebrate evolution, and may be involved in mesoderm induction and neurulation in Xenopus laevis and Oryzias latipes. To investigate the function of mammalian activins in vivo, we generated mice with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Embryonic and Fetal Development
Share to Growth Substances

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Mutation

Share to Transforming Growth Factor beta

Source

Identifiers

PMID: 7885473
DOI: 10.1038/374354a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional analysis of activins during mammalian development.PMID 7885473Read ↗

Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction.Semantic proximity Read ↗

Role of the retinoic acid receptor beta (RARbeta) during mouse developmentSemantic proximity Read ↗

Activins Are Critical Modulators of Growth and SurvivalSemantic proximity Read ↗

Different phenotypes for mice deficient in either activins or activin receptor type II.Semantic proximity Read ↗

Mice homozygous for a null mutation of activin beta B are viable and fertile.Semantic proximity Read ↗

Intertwining of Activin A and TGFβ Signaling: Dual Roles in Cancer Progression and Cancer Cell InvasionSemantic proximity Read ↗

Multiple roles for activin-like kinase-2 signaling during mouse embryogenesis.Semantic proximity Read ↗

Mice lacking all isoforms of retinoic acid receptor beta develop normally and are susceptible to the teratogenic effects of retinoic acid.Semantic proximity Read ↗

Complex expression patterns support potential roles for maternally derived activins in the establishment of pregnancy in mouseSemantic proximity Read ↗

The role of effectors of the activin signalling pathway, activin receptors IIA and IIB, and Smad2, in patterning of tooth development.Semantic proximity Read ↗

Activin C Antagonizes Activin A in Vitro and Overexpression Leads to Pathologies in VivoSemantic proximity Read ↗

Different Immunoregulation Roles of Activin A Compared With TGF-βSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.