Isolation and characterization of mutants of pseudorabies virus with deletion in the immediate-early regulatory gene.

doi:10.1006/viro.1994.1134

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Article

Isolation and characterization of mutants of pseudorabies virus with deletion in the immediate-early regulatory gene.

Virology - 1 Mar 1994

Yamada S, Shimizu M

Abstract excerpt

Pseudorabies virus (PrV) immediate-early regulatory protein (IE180) is a potent and promiscuous activator of viral and cellular gene transcription. A mutant with deletion in the IE180 gene is expected to be useful for elucidating the functions of IE180. In this study, we constructed such mutants....

Topics

Animals
Base Sequence
Cells, Cultured
Escherichia coli
Gene Deletion
Genes, Immediate-Early
Genes, Regulator
Haplorhini
Herpesvirus 1, Suid
Lac Operon
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Swine
Vero Cells

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