Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation and characterization of mutants of pseudorabies virus with deletion in the immediate-early regulatory gene.

Virology - 1 Mar 1994

Yamada S, Shimizu M

Abstract excerpt

Pseudorabies virus (PrV) immediate-early regulatory protein (IE180) is a potent and promiscuous activator of viral and cellular gene transcription. A mutant with deletion in the IE180 gene is expected to be useful for elucidating the functions of IE180. In this study, we constructed such mutants. Initially, transformants that express IE180 were established from PK-15 and Vero cells by transfection with the IE180...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cells, Cultured
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Genes, Regulator

Share to Molecular Sequence Data

Share to Mutation

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 8122367
DOI: 10.1006/viro.1994.1134

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isolation and characterization of mutants of pseudorabies virus with deletion in the immediate-early regulatory gene.PMID 8122367Read ↗

Mapping of transcriptional regulatory domains of pseudorabies virus immediate-early protein.Semantic proximity Read ↗

A TEF-1-element is required for activation of the promoter of pseudorabies virus glycoprotein X gene by IE180.Semantic proximity Read ↗

Initial characterization of 17 viruses harboring mutant forms of the immediate-early gene of equine herpesvirus 1.Semantic proximity Read ↗

Mapping of functional regions conferring nuclear localization and RNA-binding activity of pseudorabies virus early protein UL54.Semantic proximity Read ↗

Identification of Nuclear and Nucleolar Localization Signals of Pseudorabies Virus (PRV) Early Protein UL54 Reveals that Its Nuclear Targeting Is Required for Efficient Production of PRVSemantic proximity Read ↗

Inhibition of pseudorabies virus replication by a dominant-negative mutant of early protein 0 expressed in a tetracycline-regulated system.Semantic proximity Read ↗

Suppression of promoter activity of the LAT gene by IE180 of pseudorabies virus.Semantic proximity Read ↗

Construction and transposon mutagenesis in Escherichia coli of a full-length infectious clone of pseudorabies virus, an alphaherpesvirus.Semantic proximity Read ↗

A glycoprotein gX-beta-galactosidase fusion gene as insertional marker for rapid identification of pseudorabies virus mutants.Semantic proximity Read ↗

Impaired development of the cerebellum in transgenic mice expressing the immediate-early protein IE180 of pseudorabies virus.Semantic proximity Read ↗

An in vitro recombination-based reverse genetic system for rapid mutagenesis of structural genes of the Japanese encephalitis virus.Semantic proximity Read ↗

Analysis of the equalization of inverted repeats and neurovirulence using a pseudorabies virus mutant strain altered at the Ul/Ir junction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.