Article
Suppression of promoter activity of the LAT gene by IE180 of pseudorabies virus.
Virus genes - 1 Dec 2002
Ou Chia-Jen, Wong Min-Liang, Huang Chienjin, Chang Tien-Jye
Abstract excerpt
The latency-associated transcript (LAT) gene is the only viral genomic region that is abundantly transcribed during pseudorabies virus (PrV) latent infection. The mechanism of reactivation of PrV from latency remains unknown. To analyze the regulation mechanism of the LAT promoter, we constructed a series of recombinant vectors in which various sequences upstream of LAT were linked to the chloramphenicol...
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