Article
Volume changes in protein evolution.
Journal of molecular biology - 4 Mar 1994
Gerstein M, Sonnhammer E L, Chothia C
Abstract excerpt
We have determined the variations in volume that occur during evolution in the buried core of three different families of proteins. The variation of the whole core is very small (approximately 2.5%) compared to the variation at individual sites (approximately 13%). However, by comparing our resul...
Topics
- Algorithms
- Amino Acid Sequence
- Animals
- Azurin
- Binding Sites
- Biological Evolution
- Genetic Variation
- Globins
- Humans
- Models, Chemical
- Molecular Sequence Data
- Molecular Structure
- Plastocyanin
- Protein Conformation
- Protein Folding
- Proteins
- Tetrahydrofolate Dehydrogenase