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Article

Troponin-I interacts with the Met47 region of skeletal muscle actin. Implications for the mechanism of thin filament regulation by calcium.

Journal of molecular biology - 22 Feb 2002

Luo Yin, Leszyk John, Li Bing, Li Zhixing, Gergely John, Tao Terence

Abstract excerpt

Striated muscles are regulated by Ca(2+) via the thin filament proteins troponin (Tn) and tropomyosin (Tm). In the absence of Ca(2+), contraction is inhibited, whereas myosin-actin interaction and contraction can take place in its presence. Although it is well established that the interaction of troponin-I (TnI), the inhibitory subunit of Tn, with actin is required for the inhibition process and that there are...

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Identifiers

PMID: 11866508
DOI: 10.1006/jmbi.2001.5358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Troponin-I interacts with the Met47 region of skeletal muscle actin. Implications for the mechanism of thin filament regulation by calcium.PMID 11866508Read ↗

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