[Establishment of hyperbilirubinuria rat mutant--a new animal model for jaundice].

doi:10.1538/expanim1978.43.1_37

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Article

[Establishment of hyperbilirubinuria rat mutant--a new animal model for jaundice].

Jikken dobutsu. Experimental animals - 1 Jan 1994

Kawaguchi A, Nozaki Y, Hosokawa S, Tagaya O, Mikami T, Wakabayashi T

Abstract excerpt

A new animal model for jaundice, a hyperbilirubinemic rat mutant (EHBR, Eizai hyperbilirubinuria rat), was established from Sprague-Dawley rats. Hyperbilirubinemia was inherited as an autosomal recessive trait. The gene manifesting jaundice was named "hyb". Homozygotes developed jaundice immediat...

Topics

Animals
Bile Acids and Salts
Bilirubin
Cholesterol
Disease Models, Animal
Female
Genes, Recessive
Homozygote
Hyperbilirubinemia, Hereditary
Jaundice
Male
Mutation
Rats
Rats, Mutant Strains
Rats, Sprague-Dawley

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