Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Establishment of hyperbilirubinuria rat mutant--a new animal model for jaundice].

Jikken dobutsu. Experimental animals - 1 Jan 1994

Kawaguchi A, Nozaki Y, Hosokawa S, Tagaya O, Mikami T, Wakabayashi T

Abstract excerpt

A new animal model for jaundice, a hyperbilirubinemic rat mutant (EHBR, Eizai hyperbilirubinuria rat), was established from Sprague-Dawley rats. Hyperbilirubinemia was inherited as an autosomal recessive trait. The gene manifesting jaundice was named "hyb". Homozygotes developed jaundice immediately after birth, and a high bilirubin concentration was detected in plasma and urine. The plasma bilirubin levels were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol
Share to Disease Models, Animal
Share to Genes, Recessive

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Homozygote

Share to Mutation

Share to Rats, Mutant Strains

Share to Rats, Sprague-Dawley

Source

Identifiers

PMID: 8119341
DOI: 10.1538/expanim1978.43.1_37

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

[Establishment of hyperbilirubinuria rat mutant--a new animal model for jaundice].PMID 8119341Read ↗

A new mutant rat with hyperbilirubinuria (hyb).Semantic proximity Read ↗

[Genetic defect of the hyperbilirubinemic Gunn rat, a model for Crigler-Najjar syndrome type I].Semantic proximity Read ↗

New mutation causing jaundice in mice.Semantic proximity Read ↗

Age-dependent pattern of cerebellar susceptibility to bilirubin neurotoxicity in vivo in mice.Semantic proximity Read ↗

New mutation causing hereditary hepatitis in the laboratory rat.Semantic proximity Read ↗

Oxidation of bilirubin by rat brain mitochondrial membranes-genetic variability.Semantic proximity Read ↗

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced accumulation of biliverdin and hepatic peliosis in rats.Semantic proximity Read ↗

Coat-color restriction gene in rats: its effect in the homozygous condition.Semantic proximity Read ↗

[Discovery and genetic analysis of blue-eyed mutant in the white rex rabbits].Semantic proximity Read ↗

Kinetic analysis of hepatobiliary transport for conjugated metabolites in the perfused liver of mutant rats (EHBR) with hereditary conjugated hyperbilirubinemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.