Article
A new mutant rat with hyperbilirubinuria (hyb).
The Journal of heredity - 1 Jan 2000
Yamazaki K, Mikami T, Hosokawa S, Tagaya O, Nozaki Y, Kawaguchi A, Funami H, Katoh H, Yamamoto N, Wakabayashi T
Abstract excerpt
We have discovered mutant rats with hyperbilirubinuria at the laboratories of Eisai Co., Ltd., Gifu, Japan, and established a new inbred mutant strain, which was designated Eisai Hyperbilirubinuria Rat (EHBR/Eis). They show jaundice immediately after birth, and direct or conjugated hyperbilirubinemia throughout their life. The phenotypes are controlled by a single autosomal recessive gene, hyb with full...
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