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Article

Overexpression of a truncated growth hormone receptor in the sex-linked dwarf chicken: evidence for a splice mutation.

1 Nov 1993

Abstract excerpt

Sex-linked dwarfism in chickens is a form of GH resistance that resembles the Laron syndrome in humans. The dwarfism found in chickens is due to a mutant gene (dw) carried on the sex chromosome. The homozygous dwarf (dwdw) chicken is characterized by reductions in stature and plasma insulin-like growth factor-I (IGF-I) levels. Despite the absence of hepatic GH-binding activity, Southern blot analysis shows that...

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Identifiers

PMID: 8114754
DOI: 10.1210/mend.7.11.8114754

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Overexpression of a truncated growth hormone receptor in the sex-linked dwarf chicken: evidence for a splice mutation.PMID 8114754Read ↗

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Quantification of growth hormone receptor extra- and intracellular domain gene expression in chicken liver by quantitative competitive RT-PCR.Semantic proximity Read ↗

A naturally occurring growth hormone receptor mutation: in vivo and in vitro evidence for the functional importance of the WS motif common to all members of the cytokine receptor superfamily.Semantic proximity Read ↗

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