Article
Rat growth hormone receptor/growth hormone-binding protein mRNAs with divergent 5'-untranslated regions are expressed in a tissue-specific manner.
DNA and cell biology - 1 Mar 1995
Domené H M, Cassorla F, Werner H, Roberts C T, Leroith D
Abstract excerpt
In the rat, the growth hormone receptor (GH-R) gene generates two transcripts, one encoding the transmembrane GH-R, and a shorter one encoding the GH-binding protein (GH-BP). These transcripts exhibit a high degree of heterogeneity in their 5'-untranslated regions (5'-UTRs). Some of the exons encoding these 5'-UTR variants may be flanked by distinct promoter regions whose activity would result in the...
Topics
- Animals
- Base Sequence
- Blotting, Southern
- Carrier Proteins
- DNA, Complementary
- Gene Expression Regulation
- Genetic Variation
- Growth Hormone
- Kidney
- Liver
- Molecular Sequence Data