Decreased muscle cell proliferation in chicks with a deletion in the GH receptor gene.

doi:10.1677/jme.0.0170067

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Article

Decreased muscle cell proliferation in chicks with a deletion in the GH receptor gene.

Journal of molecular endocrinology - 1 Aug 1996

Goddard C, Johnson R, Gilhooley H J, Gardner J O, Gray A, Wilkie R S, Butterwith S C

Abstract excerpt

The increase in muscle weight in neonatal animals is a consequence of increased protein accretion and DNA content. GH increases protein accretion but direct effects of GH on myogenic cell proliferation have not been demonstrated. Sex-linked dwarfism in the chick is caused by mutation or deletion...

Topics

Animals
Blotting, Northern
Cell Division
Cells, Cultured
Chickens
DNA, Complementary
Genotype
Insulin-Like Growth Factor I
Muscles
RNA, Messenger
Receptors, Somatotropin
Sequence Deletion

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