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Article

Mechanism of action of developmentally regulated sea urchin inhibitor of eIF-4.

Developmental genetics - 1 Jan 1993

Jagus R, Huang W, Hiremath L S, Stern B D, Rhoads R E

Abstract excerpt

The developmentally regulated inhibitor of eIF-4 function found in unfertilized sea urchin eggs has been partially purified and its mechanism of action studied in vitro using purified recombinant eIF-4 alpha and cell-free translation systems. The results demonstrate that although the phosphorylation of eIF-4 alpha is necessary to promote protein synthesis, it is not sufficient to maintain all aspects of eIF-4...

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PMID: 8111970
DOI: 10.1002/dvg.1020140603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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