Article
Internal translation initiation on poliovirus RNA: further characterization of La function in poliovirus translation in vitro.
Journal of virology - 1 Mar 1994
Svitkin Y V, Meerovitch K, Lee H S, Dholakia J N, Kenan D J, Agol V I, Sonenberg N
Abstract excerpt
Initiation of poliovirus RNA translation by internal entry of ribosomes is believed to require the participation of trans-acting factors. The mechanism of action of these factors is poorly defined. The limiting amount of one of these factors, La protein, in rabbit reticulocyte lysates (RRL) has b...
Topics
- Animals
- Autoantigens
- Cell-Free System
- Eukaryotic Initiation Factor-2
- Guanine Nucleotide Exchange Factors
- Mutation
- Peptide Chain Initiation, Translational
- Peptide Initiation Factors
- Poliovirus
- Protein Biosynthesis
- Proteins
- Rabbits
- Reticulocytes
- Ribonucleoproteins