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Article

Interaction of the eIF4G initiation factor with the aphthovirus IRES is essential for internal translation initiation in vivo.

RNA (New York, N.Y.) - 1 Oct 2000

López de Quinto S, Martínez-Salas E

Abstract excerpt

The strategies developed by internal ribosome entry site (IRES) elements to recruit the translational machinery are poorly understood. In this study we show that protein-RNA interaction of the eIF4G translation initiation factor with sequences of the foot-and-mouth disease virus (FMDV) IRES is a key determinant of internal translation initiation in living cells. Moreover, we have identified the nucleotides...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11073214
DOI: 10.1017/s1355838200000753
PMCID: PMC1370009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interaction of the eIF4G initiation factor with the aphthovirus IRES is essential for internal translation initiation in vivo.PMID 11073214Read ↗

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