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Picornavirus internal ribosome entry segments: comparison of translation efficiency and the requirements for optimal internal initiation of translation<i>in vitro</i>

1 Jan 1995

Abstract excerpt

On the basis of primary sequence comparisons and secondary structure predictions, picornavirus internal ribosome entry segments (IRESes) have been divided into three groups (entero- and rhinoviruses; cardio- and and aphthoviruses; and hepatitis A virus). Here, we describe a detailed comparison of the ability of IRESes from each group to direct internal initiation of translation in vitro using a single dicistronic...

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PMID: 7478993
DOI: 10.1093/nar/23.18.3656

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