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Article

La protein is required for efficient translation driven by encephalomyocarditis virus internal ribosomal entry site

1 Dec 1999

Abstract excerpt

Translation of internal ribosomal entry site (IRES)-dependent mRNAs is mediated by RNA-binding proteins as well as canonical translation factors. In order to elucidate the roles of RNA-binding proteins in IRES-dependent translation, the role of polypyrimidine tract-binding protein (PTB) and La protein in encephalomyocarditis virus (EMCV) IRES-dependent translation was investigated. PTB was required for efficient...

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PMID: 10567647
DOI: 10.1099/0022-1317-80-12-3159

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