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Article

A C. elegans Hox gene switches on, off, on and off again to regulate proliferation, differentiation and morphogenesis.

Development (Cambridge, England) - 1 May 1996

Salser S J, Kenyon C

Abstract excerpt

Hox genes establish body pattern throughout the animal kingdom, but the role these genes play at the cellular level to modify and shape parts of the body remains a mystery. We find that the C. elegans Antennapedia homolog, mab-5, sequentially programs many independent events within individual cell lineages. In one body region, mab-5 first switches ON in a lineage to stimulate proliferation, then OFF to specify...

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PMID: 8625851
DOI: 10.1242/dev.122.5.1651

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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