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Article

Conditional immortalization of mouse myelomonocytic, megakaryocytic and mast cell progenitors by the Hox-2.4 homeobox gene.

The EMBO journal - 1 Oct 1993

Perkins A C, Cory S

Abstract excerpt

The murine myelomonocytic cell line WEHI-3B exhibits ectopic expression of the genes encoding the homeobox protein, Hox-2.4, and the myeloid growth factor, interleukin-3 (IL-3). We showed previously that concomitant expression of IL-3 and Hox-2.4 in bone marrow cells induced the development of transplantable growth factor-independent tumours resembling the WEHI-3B tumour. We have now investigated the effect of...

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Identifiers

PMID: 8104786
DOI: 10.1002/j.1460-2075.1993.tb06062.x
PMCID: PMC413667

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Source receipt: pubmed, retrieved 7 Sept 2026.

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