Article
Activation markers on T cells infiltrating melanoma metastases after therapy with dinitrophenyl-conjugated vaccine.
Cancer immunology, immunotherapy : CII - 1 Sept 1994
Berd D, Maguire H C, Mastrangelo M J, Murphy G
Abstract excerpt
Treatment of metastatic melanoma patients with an autologous vaccine modified by the hapten, dinitrophenyl (DNP), produces a striking immunological effect: the induction of clinically evident inflammatory responses in metastatic tumors. Histological examination shows these tumors to be infiltrate...
Topics
- Biomarkers
- Dinitrobenzenes
- Flow Cytometry
- Gangliosides
- HLA-DR Antigens
- Haptens
- Humans
- Immunotherapy, Active
- Inflammation
- Lymphocyte Activation
- Lymphocytes, Tumor-Infiltrating
- Melanoma
- Phenotype
- T-Lymphocytes
- Vaccines, Conjugate