Article
Phenotypic heterogeneity of HLA products on human melanoma cells.
Journal of immunogenetics - 1 Jan 2000
Parmiani G, Taramelli D, Anichini A, Andreola S, Cascinelli N, Fossati G
Abstract excerpt
The expression of class I and class II HLA antigens has been studied on primary and metastatic human melanomas, and on cell clones derived from the latter. A panel of monoclonal antibodies and flow cytofluorometric analysis were used to evaluate the presence of HLA-A, B, C and -DR, DQ antigens on freshly isolated tumour cells. HLA class I antigens were present on 91% and 93% of primary and metastatic tumours,...
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