Article
Phenotypic heterogeneity of HLA products on human melanoma cells.
Journal of immunogenetics - 1 Jan 2000
Parmiani G, Taramelli D, Anichini A, Andreola S, Cascinelli N, Fossati G
Abstract excerpt
The expression of class I and class II HLA antigens has been studied on primary and metastatic human melanomas, and on cell clones derived from the latter. A panel of monoclonal antibodies and flow cytofluorometric analysis were used to evaluate the presence of HLA-A, B, C and -DR, DQ antigens on freshly isolated tumour cells. HLA class I antigens were present on 91% and 93% of primary and metastatic tumours,...
Topics
- Antibodies, Monoclonal
- Clone Cells
- HLA Antigens
- HLA-DQ Antigens
- HLA-DR Antigens
- Histocompatibility Antigens Class II
- Humans
- Melanoma
- Phenotype
