Article
High levels of p53 protein expression do not correlate with p53 gene mutations in anaplastic large cell lymphoma.
The American journal of pathology - 1 Sept 1993
Cesarman E, Inghirami G, Chadburn A, Knowles D M
Abstract excerpt
Strong immunohistochemical reactivity for p53 tumor suppressor gene product has been reported in a variety of different human malignancies including CD30- (Ki-1) positive anaplastic large cell lymphoma (ALCL). Although high levels of p53 protein have been interpreted as abnormal, rapidly prolifer...
Topics
- Adolescent
- Adult
- Aged
- Antigens, Neoplasm
- Base Sequence
- Cloning, Molecular
- DNA, Neoplasm
- Female
- Gene Expression
- Genes, p53
- Humans
- Immunohistochemistry
- Lymphoma, Large B-Cell, Diffuse
