Article
High levels of p53 protein expression do not correlate with p53 gene mutations in anaplastic large cell lymphoma.
The American journal of pathology - 1 Sept 1993
Cesarman E, Inghirami G, Chadburn A, Knowles D M
Abstract excerpt
Strong immunohistochemical reactivity for p53 tumor suppressor gene product has been reported in a variety of different human malignancies including CD30- (Ki-1) positive anaplastic large cell lymphoma (ALCL). Although high levels of p53 protein have been interpreted as abnormal, rapidly proliferating benign and neoplastic lymphoid cells may have increased p53 expression in the absence of structural alterations....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.