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Article

p53 gene mutations are uncommon but p53 is commonly expressed in anaplastic large-cell lymphoma.

Leukemia - 1 Sept 2005

Rassidakis G Z, Thomaides A, Wang S, Jiang Y, Fourtouna A, Lai R, Medeiros L J

Abstract excerpt

Anaplastic large-cell lymphoma (ALCL), as defined in the World Health Organization, is a heterogeneous category in which a subset of cases is associated with the t(2;5)(p23;q35) or variant translocations resulting in overexpression of anaplastic lymphoma kinase (ALK). p53 has not been assessed in currently defined subsets of ALCL tumors. In this study, we assessed ALK+ and ALK- ALCL tumors for p53 gene...

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Share to Anaplastic Lymphoma Kinase
Share to Cell Cycle Proteins
Share to Cyclin-Dependent Kinase Inhibitor p21

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, p53

Share to Lymphoma, Large B-Cell, Diffuse

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Share to Proto-Oncogene Proteins c-mdm2

Share to Receptor Protein-Tyrosine Kinases

Source

Identifiers

PMID: 15990866
DOI: 10.1038/sj.leu.2403840

Genes

ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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