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Article

CD2 expression on murine intestinal intraepithelial lymphocytes is bimodal and defines proliferative capacity.

International immunology - 1 Jun 1993

Van Houten N, Mixter P F, Wolfe J, Budd R C

Abstract excerpt

The CD2 molecule is normally expressed on nearly all murine lymphocytes, and is co-stimulatory in T cell activation via the antigen receptor (TCR). A naturally occurring T lymphocyte population that is bimodal for CD2 expression was found in the intestinal intraepithelial lymphocytes (IEL). TCR alpha beta + IEL contain CD2- and CD2+ cells of approximately equal proportion, while TCR gamma delta + IEL are...

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PMID: 8102249
DOI: 10.1093/intimm/5.6.665

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