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Article

Possible Roles of Interleukin-4 and -13 and Their Receptors in Gastric and Colon Cancer.

International journal of molecular sciences - 13 Jan 2021

Song Xujun, Traub Benno, Shi Jingwei, Kornmann Marko

Abstract excerpt

Interleukin (IL)-4 and -13 are structurally and functionally related cytokines sharing common receptor subunits. They regulate immune responses and, moreover, are involved in the pathogenesis of a variety of human neoplasms. Three different receptors have been described for IL-4, but only IL-4 receptor type II (IL-4Rα/IL-13Rα1) is expressed in solid tumors. While IL-13 can also bind to three different receptors,...

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Source

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Identifiers

PMID: 33450900
DOI: 10.3390/ijms22020727
PMCID: PMC7828336

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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