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Article

Direct Association of Adenosine Deaminase with a T Cell Activation Antigen, CD26

23 Jul 1993

Abstract excerpt

CD26, the T cell activation molecule dipeptidyl peptidase IV (DPPIV), associates with a 43-kilodalton protein. Amino acid sequence analysis and immunoprecipitation studies demonstrated that this 43-kilodalton protein was adenosine deaminase (ADA). ADA was coexpressed with CD26 on the Jurkat T cell lines, and an in vitro binding assay showed that the binding was through the extracellular domain of CD26. ADA...

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PMID: 8101391
DOI: 10.1126/science.8101391

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