Correlation of the epitopes defined by anti-CD26 mAbs and CD26 function.

doi:10.1016/s0161-5890(98)00015-7

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Article

Correlation of the epitopes defined by anti-CD26 mAbs and CD26 function.

Molecular immunology - 1 Jan 1998

Dong R P, Tachibana K, Hegen M, Scharpé S, Cho D, Schlossman S F, Morimoto C

Abstract excerpt

To clarify the different anti-CD26 mAbs corresponding different functions of CD26, the correlation of the epitopes defined by anti-CD26 mAbs and the functions of CD26 have been studied. Using truncated, human-rat CD26 swap mutants and cross-blocking studies, 13 anti-CD26 mAbs were divided into 5...

Topics

Animals
Antibodies, Monoclonal
Antibody Specificity
Dipeptidyl Peptidase 4
Epitopes
Humans
Lymphocyte Activation
Mutation
Protein Engineering
Rats
Recombinant Fusion Proteins
Sequence Deletion
Species Specificity
T-Lymphocytes

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